Mine are definitely "To Gay or Not Too Gay" (Season 1 Ep 4) - the feels in that episode - the coming out scene was too emotional and real and "God Bless Gay" (Season 2 opener) because Tammye is a fucking icon and inspiration!
I'm finally catching up and about to start the episode where they makeover Skyler!
Mine is definitely Big Brother 10. I lived for all the drama, April/Libra/Keesha constantly fighting, an amazing female cast, Renny being a gem, Dan playing an amazing strategic game, a memorable first week, and some great house flips.