16 houseguests are confirmed to compete in this season. But 14 will be newbies, and 2 will be veterans.
After the 1st episode, America will vote which 2 will enter the house (1 male and 1 female). Supposedly these veterans are known to be leaders and or manipulators from their past season.
The 2 veterans that will enter the house will become the leaders (which means there will be 2 teams). The 1st team picks 8 newbies, and the 2nd team picks 8 newbies. The person that wins HOH will not only be safe, but that team will also be safe as well (also, the 2 leaders have immunity until the twist is over).
As for the B.O.B., it will be replaced by a new comp. The team that is in jeopardy will have a chance to compete in an immunity comp (but only 2 people from the losing team can only win it).
Even though this rumored twist sounds confusing, I do feel that it is 90% to what the twist can be. The majority of rumors I hear about this season are:
* New houseguests
* Some veterans have said on their social media accounts that they're leaving to go on vacation
* Houseguests will compete for immunity
Also I heard that this twist was going to happen in BB16. It was gonna be 8 newbies against 8 veterans. But they couldn't get any reliable veterans at that time.