I've noticed that boys typically dominate in games. I've only played Fastings and Castings, but most of the time, the guys win. Most of my alliances have only guys, and I'm the only girl. But then again, there's less drama with just guys. My alliances usually work out, too, so I guess boys rule. Either way, I like being the only girl! :)
It could be because it is a male heavy site, but it is mostly a personality thing, not a gender thing. There are some pretty catty guys, and some pretty chill girls. Personality is an unisexual thing.