Yea poor Sam. I loved Sam.
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In the alternate ending here is what happened:
Will Smiths character makes the girl mutan sick again after he takes some blood with the cure in it. Her boyfriend takes her away and then Smith, the lady, and her son leave to go find that place without sick people. You see them driving away in a van with a radio message playing. The message is that they are out there telling healthy people that they are not alone. Telling them where Smith is going. I think you can watch it on youtube. I like it better.