Mrs. Loomis, also known as Debbie Salt, is the main antagonist of "Scream 2" and the mother of Billy Loomis, she planned out the second Ghostface killing spree in order to get revenge on Sidney for murdering her son in the first film
She orchestrated the copycat killing spree with the assistance of psychopathic film student Mickey Altieri. However, Mickey and Debbie herself were both ultimately killed in the process.